邓海腾

时间:2024-01-07 09:10:27编辑:小周

邓海腾的个人简介

邓海腾,男,阿尔伯塔大学和Oak Ridge National Laboratory博士后,清华大学生命科学学院教授。

基本资料

教育背景

1985武汉大学?学士

1988 武汉大学?硕士

1996 Pennsylvania State University 博士

工作履历

University of Alberta博士后

Oak Ridge National Laboratory 博士后

1/2000-12/2001 讲师, 发育生物学系, 爱因斯坦医学院

12/2001-7/2003 助理教授, 医学系, 爱因斯坦医学院

8/2003-12/2003 助理教授, 内布拉斯加大学

1/2004-7/2009 研究助理教授, 洛克菲勒大学

9/2009-2/2011 研究副教授和蛋白质组中心主任,洛克菲勒大学

9/2008-Present ,客座研究员,纽约大学

3/2011-Present ,客座教授,洛克菲勒大学

3/2011-Present ,教授 ,清华大学

主要研究领域与方向

发展和应用蛋白质组学,代谢组学,和化学生物学的技术和方法。研究病原微生物-宿主细胞的相互作用。以细胞和小鼠为主要研究对象研究免疫细胞的抗原递呈机制并发现可能的肿瘤疫苗。发现和鉴别癌症早期诊断的标记物并研究化疗药物的毒理和作用机制。研究氧化还原生物学在衰老和疾病中的功能和作用机制。

代表性论文

1. Dun Hong, Hai-Qiang Yu, Haiteng Deng*, and Renshan Ge*Quantitative proteomic analysis of dexamethasone-induced effects on osteoblast differentiation, proliferation,and apoptosis in MC3T3-E1 cells using SILAC, Osteoporosis International 2011;22:2175-86.

2. Qingli Shi, Hui Xu, Haiqiang Yu, Yaozu Ye, Alvaro G. Estevez, Haiteng Deng and Gary E. Gibson, Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex, Journal of the Biological Chemistry, 2011;286:17640-8.

3. Kabirul Islam, Weihong Zheng, Haiqiang Yu, Caitlin Sengelaub, Haiteng Deng and Minkui Luo, Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling, ACS Chem. Biol. 2011;6:679-84.

4. Chongdong Liu, Nawei Zhang, Haiqiang Yu, Zhenyu Zhang*, and Haiteng Deng*, Comprehensive Serum Analysis for Finding Pathogenic Factors in Preeclampsia, Placenta 32 (2011) 168-174.

5. Uttiya Basu, Fei-Long Meng, Celia Keim, Veronika Grinstein, Evangelos Pefanis, Jennifer Eccleston, Tingting Zhang, Darienne Myers, Duane R. Wesemann, Kurt Januszyk, Richard I. Gregory, Haiteng Deng, Christopher D. Lima and Frederick W. Alt, The RNA Exosome Targets the AID Cytidine Deaminase to Both Strands of Transcribed Duplex DNA Substrates, Cell 2011, 144, 353u2013363.

6. Lina Cheng, Jiayin Zhang, Sana Ahmad, Lorene Rozier, Haiqian Yu, Haiteng Deng, and Yinghui Mao, Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment, Developmental Cell 2011, 20, 342u2013352.

7. Doina M. Mihaia, Haiteng Deng, and Akira Kawamura, Reproducible enrichment of extracellular heat shock proteins from blood serum using monomeric avidin, Bioorganic & Medicinal Chemistry Letters 2011;21:4134-7.

8. Rui Wang, Weihong Zheng, Haiqiang Yu, Haiteng Deng, and Minkui Luo, Labeling Substrates of Protein Arginine Methyltransferase with Engineered Enzymes and Matched S-Adenosyl-l-methionine Analogues, Journal of the American Chemical Society 2011, 133, 7648u20137651.

9. Bozzacco L, Yu H, A Zebroski H, Dengjel J, Deng H, Mojsov S, Steinman RM. Mass spectrometry analysis and quantitation of peptides presented on the MHC II molecules of mouse spleen dendritic cells. J Proteome Res. 2011;10:5016-30.

10. Xie T, Ren R, Zhang YY, Pang Y, Yan C, Gong X, He Y, Li W, Miao D, Hao Q, Deng H, Wang Z, Wu JW, Yan N. Molecular mechanism for the inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by the protein phosphatase ABI1. J Biol Chem. 2012;287:794-802.

丛书章节

Amanda Chen, Haiqiang Yu, Haiteng Deng and W. Beau Mitchell, Mechanisms of αIIbβ3 Biogenesis in the Megakaryocyte: A Proteomics Approach in Hematology - Science and Practice, Edited by Charles H. Lawrie, ISBN 978-953-51-0174-1, Publisher: InTech, March 02, 2012 DOI: 10.5772/2259.

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